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Preserve biological complexity. Achieve molecular resolution.

Understanding how the disruption of membrane organization and signaling contribute to human disease.

Chronic Pain

We study how specific states of TrkA signaling lead to nociception versus neurotrophic outcomes, guiding new strategies for
non-opioid pain therapeutics.

Examples:

  • Nerve injury

  • Neuropathic pain

  • Inflammatory pain

  • Cancer pain

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Neurodegeneration

We investigate organellar membrane proteins and contact sites that maintain neuronal health and explore what goes wrong in disease.

Examples:

  • ALS

  • Alzheimer's disease

  • Parkinson's disease

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